I have never used Celexa. For more info on this drug (it's a brand name) click on this: http://www.rxlist.com/cgi/generic/citalo.htm The antidepressants I've used do have to be adjusted. I'm not familiar the adjustment of BuSpar since at appropriate dose that my Doc had me on had no real effect on me so I discontinued its use. I recall reading on the IBS BB that BuSpar allows the colon to expand in size to allow for stool formation. I don't know if this is true.I suggest you consult with your Doc and perhaps the medication itself will be changed.Good luck!