My GI emailed me and told me of a patient of hers that went to see a complimentary doc for ibs and interstitial cystitis. This doc gave her d-mannose. My GI could not believe how well this made her feel. She told me that in reading about it, she felt that maybe it could be of use for SIBO/IBS.I am afraid to try it as I fear it could cause gas. This is a top GI by the way.