[kaj]

Hello Mike, I use to post on the IBS Board regularly, but have been off for a few years. I posted on the Gas/Bloating board the other day about sugar being a problem food for me and someone suggested I look at the Food/Nutrition board - I didn't even know all these different boards were here - I even briefly looked at the Leap site last night and found it very interesting - will make a second longer visit tonight and make my way through all the Leap threads on this board.But, I have a question and you may not be at liberty to divulge the answer or know it for that matter, but I was interested what the most common food/drug was that seemed to be the most intolerant? Thanks Kirsten

 

[ohnometo]

bump for Mike to see

 

[Mike NoLomotil]

KAJ:Sorry to take so long just like you don't get around as much as I used to....kinda busy these days with some other projects as well.This is a tough question to answer as unlike allergies there is no BIG DOG as afr as the patterns of cellular lost tolerance as assessed by release of inflammatory mediators (no IgE).In other words there is no food that has such a statistical probability of producing a hypersensitivity reaction that if you took 500 IBS patients and just rmeoved it from their diet, say 70% would feel better long term (short term placebo affects will wane after a few weeksa nd you can see consistent symptom reduction).BUT in food hypersensivity often the reactions are related to lost oral tolerance linked to overconsumption. So in this country we see probably wheat and whole milk reactivity alot, as we eat a lot of it as a people (Got milk? Got diarrhea?) whereas in the United Kingdon, for example, you cans ee a higher frequency of intolerwnce to things like beans...which is very popular and consumed heavily.But if you look at the frequency charts, especially the last sevearl years, its all over the board.One of these dys I will have the engineers run a new frequency analaysis and then put it out there for everyones interest...as the one I used before may only be valid for this part of the country as the databse was primarily south Floridians during technology development.Now we have a good cross section of the country and the distribtion may be different. I won't forget the interest in this.MNL