I was diagnosed with IBS-D three years ago after a sudden onset diarrhea. The last year, I have been having pain under my right ribs just at the lower edge of the right rib cage, along the edge of ribs on the rights side. My pain is sometimes dull and sometimes stabbing. When making a sudden move like twisting towards back or if I bend sideways to the right, I sometimes get a stabbing pain unexpectedly. At times, it feels as if there is something under my ribs. Often my entire upper right quadrant is sore as if I had a bruise from something that hit me. Sometimes I can localize the pain at a specific spot, right at the edge of my right ribs sometimes it is more diffuse but still in the general area. It almost feels as if there is a tumor growing in the area. These sypmtoms have been so relentless and so specific that I was convinced that there was something wrong, perhaps with the liver, biliary ducts or gallbladder or even the head of the pancreas. However, my recent MRI came up normal. The reason I am posting this is to let others who have similar symptoms know that despite the unmistakable, persistent, very specific and localizable pain in that area there may be nothing serially wrong with you. I know that I am not imagining my symptoms. This pain may be due to subclinical low grade inflammation of the large bowel at the hepatic flexure extending towards the right side of the traverse column or a low grade inflamation due to a lingering infection of the large bowel or the Sphincter of Oddi (check out Sphincter of Oddi dysfunction). Subclinical inflammation does not show up in MRI or even colonoscopies and pill endoscopy. If you are having similar systems don't assume the worse automatically but go get yourself checked. As a side note coffee aggravated my symptoms. I hope this helps. Feel free to ask me any questions about my symptoms. Wishing you all the best.