soccer mom,Your rebound D is very common with a lot of us I think.In fact, I follow something very similar to your med pattern with Lomotil and imodium, and I experience rebound D sometimes. Interestingly, sometimes I don't. That's one of the many confounding characteristics of this curse: you can't ever be sure it's caused by the same thing each time. I mean, one time I'll follow exactly the same pattern (e.g. take two Lomotil on Tuesday, and then not again until Friday) as the last time, and one time it results in rebound D and the next time it doesn't. I think a lot of it depends on diet and intake volume during and after the dose. Problem is, I get so hungry and I think that since I have a day or two with no appointments, I can eat what I want. That attitude usually results in a rebound D episode.Now before I got the Lomotil prescription, I was using the imodium only. It worked, but I almost ALWAYS got a rebound episode. When I told my doc about that, that's when he prescribed the Lomotil. He said that the Lomotil worked just as good, maybe even better, and would not result in as many, or as severe, rebound D episodes. He was right. I still use both, depending on the circumstances and the time I have to control, but the Lomotil does result in fewer and less severe rebound D episodes.In any case, your description of symptoms and meds is very very similar to my situation. Good to see there is someone else out there with the same circumstances.I'm hoping one of the new drugs coming out will solve this rebound problem for us.BJP.S. I also do the Caltrate, which does help, but is not "perfect".P.P.S. Rebound D, as I understand it, is in fact an explosive IBS-like BM that happens sometime after a dose of one of those meds (like imodium or Lomotil) "wears off".