sorry to say it IS the remeron in and of itself. then, on top of that, it's remeron's antihistamine properties that also kick in the desire to binge, esp. on carbs & sweets. remeron is an excellent drug for ibs, anxiety, and some find it enough for depression. it's been claimed it's the opposite of most ads - at the higher doses of 45-60 mg, it supposedly stops or decreases the weight gain. i have not found that to be the case + at above 30 mg many users lose the anti-anxiety and good sleep help it provides. also high doses can cause anger to emerge. a real shame, as it's so calming to the GI tract -upper & lower.