I came across this article and thought it might be of interest: Role of DietAnother intriguing area that is currently undergoing more active exploration, is the potential role of dietary modification in IBS. There has, however, been a lack of population-based studies evaluating nutrient consumption in individuals with and without IBS.Saito and colleagues presented their findings from a case-control study conducted in Olmsted County comparing dietary consumption of specific nutrients in subjects who had a presumed functional gastrointestinal disorder with controls (ie, those without symptoms). A validated food frequency questionnaire was applied. Patients with functional gastrointestinal symptoms consumed a higher percentage of fat, but there were no other major differences observed between the 2 groups, although there was a modestly lower percentage of carbohydrate, vitamin C, and sugar consumed by individuals with functional gastrointestinal complaints.Drisko and colleagues performed an open-label study evaluating 20 patients with a history of IBS with diarrhea who failed standard medical treatment. Patients had a food-elimination diet provided for 1 month based on the results of serum IgE and IgG food and mold panels. In addition, probiotics were provided in months 2-5 during controlled food challenges. Of the 19 patients who completed the trial, there was significant improvement in terms of pain, stool frequency, and quality of life after the intervention. However, this was not a controlled trial, and therefore the results require confirmation in randomized clinical trials.A controlled trial of food-elimination diet demonstrating promising results was reported during Digestive Disease Week 2003. In this study, 150 patients were randomized to either receive a diet excluding all foods to which they had positive IgG antibodies or to a sham exclusion diet. The investigators observed that symptom severity scores were significantly reduced in the active-therapy arm. The role of withdrawal diets in IBS remains to be adequately documented, but this strategy represents a nonpharmacologic approach to management that may be useful.