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serotonin levels, Mao levels among the anxious men of India with IBS-D.Correlation of serotonin and monoamine oxidase levels with anxiety level in diarrhea-predominant irritable bowel syndrome.Singh RK, Pandey HP, Singh RH.Department of Biochemistry, Faculty of Science, Institute of Medical Sciences, BHU, Varanasi 221 005. rakeshbhu###yahoo.comBACKGROUND: Irritable bowel syndrome is generally considered to have a psychogenic component in its physiopathology. AIM: To study the role of serotonin 5-hydroxytryptamine; 5-HT, monoamine oxidase MAO and anxiety, and to elucidate the relationship between these in patients with diarrhea-predominant IBS. METHODS: 5-HT and MAO activity and anxiety levels were studied in 20 healthy volunteers aged 18-25 years; all men and 57 patients with diarrhea-predominant IBS 30-60 years; all men. RESULTS: The concentrations of 5-HT and MAO , and the anxiety level score were significantly higher in patients than in healthy volunteers , 6.4 and 3.4 , respectively. These parameters correlated with each other in both patients and volunteers. CONCLUSIONS: Elevated 5-HT and MAO activity and anxiety may play a role in patients with diarrhea-predominant IBS.tom
 

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Tom,This reminded me of a statistic that used to appear ages ago on the BB, namely that, apparently, India was the only country in the world where men outnumbered women in the prevalence of(reported) IBS cases.So it's good to see they're doing research into it!
 
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