I was on Lotronex a few years back, only for a month, as soon as I figured out my dosage I should take, they took it off the market. I was down to a half a pill aday and it was working really well for about 2 weeks. I started out on the recommended dosage and it gave me really bad cramping and constipation, which I never thought in the past 11 yrs that I would ever get constipated again after suffering from cronic "D" I go to the doctors this Friday, I'm thinking about asking for the lotronex again, I am presently on Hyoscamine, and I take calcuim, but the hyoscamine doesn't seem to be helping me much these days..I've been on it for over 3 yrs. Has anyone been on the lotronex recently? and if so..tell me what you dosage is and if it really helps you?