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I took printouts of the recent threads about Pimentel and SIBO, as well as some of the cited studies to my GI, and he agreed that it’s a strong possibility. He also said that many GI specialists used to prescribe antibiotics, often successfully for IBS. Anyhow, he offered to put me on Cipro for ten days, just to see how it works. He said he’d be willing to do the Pimentel protocol if he had Pimentel’s exact drug regimen from Pimentel himself. I emailed Pimentel, but haven't heard back yet.So, in any case, I’m 3 pills (36 hours) into the ten-day Cipro trial, and I still have gas. My primary symptoms are gas, bloating, and abdominal distention. I didn't take the breath test: GI felt it's not necessary.Here’s my question: for those of you who have responded to antibiotics, even accidentally (like for a sinus infection, etc) how long were you on the antibiotics before your IBS symptoms really improved?
 

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Been on Cerufoxime for 10 days and in the second week i was able to eat anything!I still have IBS and it comes rigth back after the course of anti-antibiotic.It was for a sinusitis.
 

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Yes.You need to get the things moving after the course.Maybe with Erythromycin,i don't know.
 

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Where are you from?
 

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There is a lag between taking and stopping antibiotics and seeing the resolution to your symptoms by as much as two weeks. To know for sure that the a/b have helped you need a before and after lactulose breath test.
 

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To Spas, thanks for getting back to me.I'm from northern California--Oakland. To Bonniei, I've seen your previous posts about the lag time. I'm a bit hesitent to believe that's very common. It seems to me that if the antibiotics work, then the symptoms will disappear. I've read a lot of anecdotal postings on this board about antibiotics temporarally helping symptoms. If the symptoms return after having been cleared up, it simply sounds to me that the bacteria have not been completely irradicated and have returned. My goal is to take the full month-long Pimentel course and just wait and see. If the symptoms return, then i've still got a problem, wich is pretty much what the breath-test would tell me.Much of what i have read suggests that GI researchers aren't really in agreement about the validity of the breath tests anyhow. For me, clearing up symptoms is the gold standard. In any case, i still have symptoms, so I don't want to get ahead of myself. Can anyone else tell me about their antibiotic experiences?
 

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quote:To Bonniei, I've seen your previous posts about the lag time. I'm a bit hesitent to believe that's very common. It seems to me that if the antibiotics work, then the symptoms will disappear
Well I think I can safely say that the Cedar-Sinai researchers,Pimentel and Lin have done the most extensive prescribing of antibiotics to IBS'ers and the observation that it takes upto two weeks to clear up is based on their research. It is all in this paper.http://www.ncbi.nlm.nih.gov/entrez/query.f...2917&query_hl=3It costs $25 to purchase if you want to see it for yourself or a library near you may have a copy. They did the before and after breath tests on these patientsa and found that even after normlization of the breath test after the course of aniibiotics the symptoms did not seem to resolve and they observed in these patioents that the symptoms did resolve after two weeks. They tested atleast 150 patients till Jan 2004 and even more since then before they made this statement. They weren't going on the basis of hunches.
 

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I'm curious too about which IBS this is for. I read the long thread SIBO, but in some cases it sounded like it was mainly for IBS-C, not D (or possibly it was for C and A).I have D. It's something I am going to bring up with my doc. Makes sense to me since I get the bloating, gas, etc. Haven't been on AB for a LONG time. But I do remember some relief and a good "cleanout" a couple days after starting to take it.
 

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Yes I have the paper. It says symptoms can even worsen for a couple of days 3-4 days into the treatment. And the complete resolution of gastrointestinal symptoms may take as long as 2 wks while the extragastrointestinal symptoms like fatigue, general malais, myalgia, anxiety, depression and even impaired cognitive function might take up to 2 -3 mths to resolve. It doesn't say what percentage of patients took upto 2 wks for the symptoms to resolve. So yes that is good news for you.
 
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