Well I think I can safely say that the Cedar-Sinai researchers,Pimentel and Lin have done the most extensive prescribing of antibiotics to IBS'ers and the observation that it takes upto two weeks to clear up is based on their research. It is all in this paper.http://www.ncbi.nlm.nih.gov/entrez/query.f...2917&query_hl=3It costs $25 to purchase if you want to see it for yourself or a library near you may have a copy. They did the before and after breath tests on these patientsa and found that even after normlization of the breath test after the course of aniibiotics the symptoms did not seem to resolve and they observed in these patioents that the symptoms did resolve after two weeks. They tested atleast 150 patients till Jan 2004 and even more since then before they made this statement. They weren't going on the basis of hunches.quote:To Bonniei, I've seen your previous posts about the lag time. I'm a bit hesitent to believe that's very common. It seems to me that if the antibiotics work, then the symptoms will disappear