I have literally had constipation issues my whole life. I go about once a week. I have tried everything including zelnorm which made me crampy and all natural supplements made me crampy. I now have low B12 levels which my Dr. thought was malabsorption but a gastro told me that i was fine. I just ordered Dr. Natura - hoping it would do something for me, even if temporary. Anyone have any suggestions for me? Help!!!