I am going through this werid phase--here goes...I was put on Zoloft and diagnosed with IBS 8 years ago...For the past 3 months I have been off of the Zoloft and put on Effexor---BAM all my symptoms were gone and I havent felt better moving by bowels normally no symptoms at all---I thought I was cured----Now for the past 2 weeks I have been very gassy and constipated and not a very happy camper..Could my symptoms have been hiding and now coming out the opposite with the gas and constipation....I really thought it was the Zoloft that was making me sick......Has anyone else ever experienced this? Thanks for your help-----------Chris