Good lord, I've been off the board for about a year, and came in to answer a question that I got in a private message.When person asked me "why do bacterial researchers say start with antibiotics and then move to probiotics?" I wondered if she was talking about Ian Ramsay bacterial expert researcher, extrordinaire. See my thread from last year: http://www.ibsgroup.org/forums/index.php?showtopic=102286I'm not going to get sucked back into a debate about this. As far as I know I am the only person on here who actually went to the trouble of summarising all his knowledge and research about how he beat SIBO, including citations and links where I found the information and how I applied it to cure my SIBO. Cutting out probiotics was pretty fundamental and is recommended by Pimentel. Pimentel says in no uncertain terms that although probiotics appear to allevitate the symptoms, they only serve to prolong the disease. Read the quotes and the citations in the post. Ian says in page 5 that he's got a leaky IC valve. so his situation is not even relevant to a normal SIBO case!!!The only further piece of knowledge I would add to my previous post..... A lady messaged me to tell me that she had successfully beat SIBO, the bad bacteria were gone from her small intestine (negative HBT). But she still had symptoms so she tried a high colonic hydrotherapy which she did at home using her shower hose or something (if you do this I would suggest sterilising the pipe first - maybe let the hot tap run for a couple of mins before cooling it down for use). She said after she did this she had perfect digestion for 2 days but then her symptoms gradully came back. I said to her "that would indicate you've got bad bacteria in your LARGE intestine as well" - perhaps c-diff from the antibiotics or maybe just the bad bacteria E-Coli or whaever was still in her large intestine in high numbers. I said try doing it every 2 or 3 days, then every 4 days keep flushing out the toxins & bacteria before they have a chance to return. And after about 3 weeks doing this she said she said she had gone for over a week with perfect digestion and didn't require any more colon hydras. So basically in the case of this lady, the antibiotics HAD got rid of her SIBO, but either because of the antibiotics or just the E-Coli (or whatever) that caused the SIBO her colon bacteria were all screwed up. But she never ever used probiotics. Actually since I wrote my original post they have since discovered that the purpose of the Appendix is to replace gut flora: http://www.msnbc.msn.com/id/21153898/ so there is absolutely no reason to take probiotics at all - the small intestine is sterile (supposed to have no bacteria). And the large intestine is replenished from the appendix.Me, I've never touched a probiotic since I wrote the post and I never ever ever ever ever will again. Oh and one last tip I start every day with a bowl of oats boiled in water till they go thick. I put a tiny splash of milk in the bowl. I feel these scrape my intestines clean every day and absorb any bad toxins out of the gut and gives me good regular bowel movements once a day. Just think.... before all this 'good bacteria' 'probiotic' stuff that sprouted up about 20 years ago, did you ever hear about IBS? Parents/Grandparents? People in history? What if these probiotics are actually causing all this in a new generation of health conscious adults? - I don't know - maybe? I think probiotcs are the most unnatural thing you can ingest. Our species evolved over Millions of years without probiotic pills, so we don' t need them now either.Anyway, good luck everyone! I'm bailing out now. I lost most of my 20s to this disease. I'm 30 next month and I can't quite believe it - I feel that there is a gaping void in my life that I lost to IBS/SIBO and I'm like 'woah how did this happen?' I'm making the most of life these days Life is good, I started a business which has just started making profit, I can bench-press my 1.5 times my body weight and I've got tons of energy and a spark for life. You will get this back eventually too!If anything I hope my success gives you hope. You can beat SIBO - I lived with it for 8 years!Good luck, keep the faith, you'll beat it eventually! http://www.ibsgroup.org/forums/index.php?showtopic=102286Bye!