Shelley,I have been on the Serzone for over amonth now. For the past two weeks, I have been on 200 mg's a day. It is hard to know is antidepressants are working because you don't know how you are 'supposed' to feel. People think it is a 'happy' pill, but I think it just makes you feel NORMAL. I am feeling much less obsessive and anxious for the past few weeks. At first while taking it, I felt sleepy, but I think lately, I have had more energy than ever. I took it mostly for general anxiety which ahas subsided A LOT! I am mostly C which alternates with D. The main prob with that is that I never know when D is going to hit, so I am anxious a lot cuz I feel gurgley all the time. Never know when I will need the bathroom. It has not really done much for my IBS. At first I thought maybe it was helping, but you know how IBS is, one week good, three weeks bad. . . . .I have had good results so far with the Serzone. I will warn you, it is really expensive. and my inusrance has not been covering it. I took paxil for four years, and it works very well for anxiety, depression, etc. It kills your libido which I couldnt take being that I am 23. I still havent got it back, and I have been off paxil for six months. Who knows, good luck,LALAS