I'm scheduled for my 2nd colonoscopy after 14 years. I recently turned 40. I'm wondering if it's really neccessary, and am trying to weigh the risks. The tests I've had thru the years have always come out normal - diagnosis IBS. I'm IBS-C and lately have had a sharp pain in my lower right abdomen that comes and goes, and is more prominent with movement. I'm also severely constipated and have pain with a movement. The gastroenterologist said that I should have another colonoscopy because it was so long ago since my last. Have any of you had more than one? Should we get checked-out ever so often? My flare-ups seem to be every 7 years. Is "peace-of-mind" worth the risk of something going wrong during the procedure? I'm nervous about the whole thing. My father died of bile-duct cancer last year at age 64, and my boss died 3 years ago with colon cancer at age 57. I wonder if my symptoms are just from stress and worry.