Apparently I posted this on the wrong place.. OPPs! I have just had my worst bout ever with IBS. I had a complete work up and nothing unusual was found. Although I've had much milder bouts with this in the past, I never lost weight before. My Dr. Seems concerned about this weight loss and a little uneasy about writing my symptoms off to IBS. (I'm the D type) I have always been somewhat overweight and have had about a 15 lbs. weight loss in the last couple months. I also wanted to say that I've begun taking Clatrate today and hope to give you positive results soon!!! I think this is a great site, I,ve never learned so much before!!