Well not to discourage you, but my IBS surfaced when I first started taking Wellbutrin for ADD (doctor wanted to try this before stimulants). Now, was Wellbutrin the cause of my IBS? Probably not, but I will never know for sure, but the way I reacted to Wellbutrin I might as well have been smoking crack. It honestly felt like I was taking a hallucenogenic drug sometimes when I was on it. I cannot say 1 positive thing about it. I was constipated the entire time I was on it though, so it may help you in that aspect.There are a lot of Wellbutrin horror stories out there if you search about it on the net, but it has obviously helped a lot of people too. I am also very sensitive to medication like you. Wellbutrin was just hell for me and I still regret that I tried to tough it out and took it for over a month.