I have had ibs-D for years and years so bad that I do not eat out at all. Keeps traveling out of the question. ANYTHING can bring it on out of the blue with absolutely no warning... which means lots of accidents. My life had become almost that of a recluse and depression set in in a big way. I have tried SO MANY things, gotten my hopes up to have them dashed again and again. I just started wellbutrin Xl about 3 weeks ago. On exactly the same day, I was treated by another doctor for inner ear fluid that would not go away with triamterene, which is evidently like a diuretic (Sp?)/ low blood pressure pill. I don't know if this is a fluke or not, but I have not had a problem with diarrhea for the past three weeks. I am almost scared to even think this will maybe work after all of these years. I am holding my breath. Has anyone ever heard of this working? I don't know if it is one or the other since I started both on the same day. Could it be possible that a simple diuretic could help ibs-d? Do you think it could be absorbing excess fluid and releasing it through urine instead of constant D? Just curious....