NO! Sorry to shout, but this drug caused me more problems than anything else. I was IBS C/D before I started taking Wellbutrin, but the drug made my C soooo much worse. I have had MAJOR problems with fissures ever since; well, it's really the same fissure that just has never healed. This has been going on since February. The worst was in July, when I developed a rectal abscess--the fissure got infected, leading to god-awful pain. I had major surgery in 99, and that pain was not as bad as what I went through in July.I never, ever should have been on Wellbutrin, in all honesty. I didn't catch on to this at the time, but I now believe my ex-dr. thought that, to some extent, the IBS was in my head. She kept asking if I was obsessive-compulsive and assumed I was in a major depression. She knew I was in therapy, which I started in 98 when I did indeed have a major depression triggered by my grandma's death. My therapist even talked to my dr., telling her that yes, I was in therapy and working on some issues, but no, I wasn't depressed, hadn't had a depressive episode in almost two years, and didn't need to be on an anti-depressant for psychological reasons. In fact, I didn't use anti-depressants when I experienced my depression during 98! The dr. resassured her and me that she was putting me on the drug for my IBS, but later it became apparent that she put me on it for psychological reasons. The dr. told me to only take it for five months and by then I should be "feeling better." When I said to her, "IBS is a chronic condition--how is it going to go away in five months?" she stammered a bit and then said something like, "Well, by then the stress will be gone." Mind you, this was during a very happy period for me--I had just been accepted to every Ph.D. school I'd applied to and was receiving very generous offers. But, wanting to be a "good patient," I trusted her and did what the dr. said. At one point, I was taking 8 fiber choices a day (that's the equivalent of 4 glasses of Citrucel!, drinking 80 oz of water and still couldn't go to the bathroom, only to be told to keep upping my fiber and water because I "needed" the wellbutrin. All I could think was, "For what?" This drug was supposed to help my IBS, not make it worse, and I was not depressed. I finally said "screw this" and quit taking the drug in June. It takes a long time to get anti-depressants out of your system; my bowels are just starting to return to "normal." Sorry to just explode in this post, but this topic is a very sore subject with me. Everyone is different, and perhaps the drug will be beneficial to you. It was an incredibly frustrating experience for me, though, as I did everything "right" (diet, exercise, fiber, water, etc), yet had the worst C of my life. Just be very careful and make sure your doctor is being honest about why you need this drug. Many people on this board and in the world, for that matter, need anti-depressants for both psychological and physical reasons, and they should definitely take them! However, no one should be misled into taking anti-depressants, as I was. And, if you would experience bad side effects, inform your doctor and make sure he/she LISTENS. My doctor did not listen to my concerns, and I let myself be talked into damaging my health. If your doctor dismisses your concerns, RUN, don't walk, to another doctor! As I learned a little too late, we must be our own advocates because the doctor does not always know best (especially when it comes to our own pain and suffering).