Hi all, been off the boards for awhile, glad to be back. When I joined the boards, I was suffering from IBS-D, horrible cramps, urgency,lost my appetite, lost quite a bit of weight, you know the routine.. In the past I have been treated with Sinequan, Librax, Lomotil (yuck), Immoduim AD, Bentyl, Levsin SL, with the Librax being the most recent one. I joined the board to look for alternatives, conversation and understanding people-found it all here) I had read alot about the L-Glutamine people were trying for Diarrhea, and decided to try that, and that alone. I went to GNC and bought the powder form, started at one teaspoon in a glass of water (relativley tasteless), and almost immediatley the diarrhea resolved itself. I went two days with no BM, then began to have one every morning, with the normal warning signs, no urgency, and no cramps. Just trying to be the inquisitive nurse that I am, I stopped the L-Glutamine after one week, I remained normal for about a week, then I started right back with the diarhhea pattern. Is it totally related? Who knows? Close enough for me though, so I am not suggesting everyone run out and try it, but it is an option that worked well for me. The L-Glutamine research that I did was very promising and positive. I am not against people taking prescriptions, you should do what works for your body, but after all the prescriptions I had taken, I wanted something else. L-Glutamine apparently has many many claims to conditions that it "may help with" such as obesity, alcoholism, tissue repair, on and on. I did not read bad things about it, not saying they don't exist, but that was a plus for me. Like I said, it was what I needed, I have had no issues with it, and it is merely a suggestion, and testimonial if you will lol!Wishing the porcelain God will have mercy on the ring around our butts!