In my case, staying away from high fructose corn syrup has meant the following improvements:1. Only 1-2 trips to the bathroom a day vs. 2+2. Less cramping (MUCH less)3. More energyKeep in mind that even if HFCS doesn't bother you, the foods which contain it are almost all junk anyway. Some breads and cereals are likely exceptions to that rule, but if too many of your calories are coming from HFCS, you might want to think about dietary changes regardless of IBS!