Which antidepressent helped you best for your IBS ? Especially for abdominal discomfort/pain. I am currently taking 60mg Celexa and sometimes I think it's working a bit and other times I don't think at all. I can't even tell anymore. I have diarrhia maybe only once a month but mostly I have frequent stools which don't give me much relive. I am also very anxious and depressed about my IBS. I can't picture my life always being like that. My husband pretty much ingnores me when I am sad. Sometimes he tries to cheer me up and since it mostly doesn't work he gets upset with me. Than the whole thing makes me even more depressed because I can't cheer up on command when I don't feel good. There is just no support. I have to feel guilty for feeling sick. What other antidepressetns should I try ?