My doc assures me that IBS does not lead to cancer or Crohn's. That being said, I have no knowledge about how new this disease is, if it is in fact a new phenomenon. (That is one of my eternal questions - did this condition exist decades ago and nobody ever talked about it? Or is it caused by something new?) So, if it is new, how do they know what it leads to or not? And further, I now have two perianal fistulas, which my surgeon says could be caused by chronic diarrhea, and maybe not. My confidence in the science and practice of medicine has taken a steep nosedive in the last several months. Nobody knows anything, and we just stay sick, or get sicker. I'm fed up with the whole shebang, and ready to spit.