I've tried triphala and it has made a world of difference to me. It makes me almost normal; I don't take the full dosage which they say is 3 capsules a day (I only take 1) and n o complaints. I don't know about the other ingredients, but then I try to take as few pills as possible -- that's what got me into this mess to begin with. Good luck, but I would watch the cascara -- I hear it can cause problems after continual use -- like weakening bowel muscles (or so my gastro told me).