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Discussion Starter · #1 ·
I got my RX filled for Lotronex today. I am praying to God in Heaven above this will help me. I first called the pharmacy, they said they had it in stock. Then I called my insurance, they said it was covered. Then I called my Dr. and they approved the RX, then later called back and asked what the doseage was supposed to be, so I told them one pill twice daily. They asked where I got the info and I told them the Glaxo site and here as well as the other IBS BB. It cost me $15 for 60 pills and I even got 1 refill! I took one tonite. So far so good, although it's early yet. I'll stay in touch to let everyone know how it goes. Yahoo!!
Tamme[This message has been edited by tbear (edited 03-06-2000).]
 
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congrats on getting the Lotronex. I can't wait to see how things go for you. I have to wait until I'm through with my pregnancy and breast feeding before I can try it, but I can't hardly wait. I think I'm going to start the fight now with my insurance as I'm sure they will deny it at first.Thanks for the info and look forward to your progress reports.Christine
------------------It is never too late to be what you might have been.----George Eliot
 

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Discussion Starter · #3 ·
Hi all. Day four and everythings going good with the Lotronex. No more cramping and the D is still slowing. I feel more able to get up and out and do things now. Yahoo.Tamme
 
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Yes tbear keep us posted. I am catching up on all my reading on the post this evening and I go see the doctor in the morning. I'm going to talk to her about Lotronex, HOWEVER, I am what they call a "part-time" ibs-d person. I only have these D attacks maybe 2 to 3 times a month. I do not have D every day. I still wonder if it will help because I am one of those C a couple of days, D the rest.Hmm, any advice?Thanks everyone!-ShellyAnn
------------------They don't call me an all terrain turtle for nothing!
 
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Title: DG DISPATCH - DDW: Lotronex Promising As IBS TreatmentURL: http://www.pslgroup.com/dg/FEACE.htm Doctor's GuideMay 19, 1999By Andrew BowserSpecial to DG NewsORLANDO, FL -- May 19, 1999 -- A new therapy under investigation for women with irritable bowelsyndrome (IBS) provides significant relief from pain and discomfort, according to multicentre phase IIItrials reported yesterday at Digestive Diseases Week, in Orlando, FL. GlaxoWellcome's drug Lotronex (alosetron) binds selectively to 5-HT3 receptors, which may cause aslowing in colonic transit, as well as a reduction in transmission of pain signal from the colon. In one 12-week trial of 647 non-constipated women with IBS who took alosetron twice daily, morethan 60 percent of patients experienced relief as measured by a composite pain and diarrhea scale.That compared to somewhat more than 40 percent of patients who received a placebo -- a statisticallysignificant difference. A second, similar randomised controlled trial including 626 non-constipated women with IBS showedsimilar results. The drug's efficacy is not limited to women, said Dr. William Chey of the University ofRochester in Rochester, N.Y. Dr. Chey described the case of a 39-year-old male executive with unexplained abdominal pain andfrequent bowel movements who couldn't tolerate the side effects of conventional anticholinergictreatments (which include blurred vision, dry mouth and inability to concentrate). After startingalosetron, the executive's pain improved and his symptoms were markedly reduced. Composite clinical trials including men and women are underway. In addition, Glaxo Wellcome plans tofile a New Drug Application with the U.S. Food & Drug Administration within a month or two.--------------------------------------------------------------------------------------------- Copyright � 1999 PSL Consulting Group Inc. All rights reserved. Republication or redistribution ofPSL content is expressly prohibited without the prior written consent of PSL. PSL shall not beliable for any errors, omissions or delays in this content or any other content on its sites, newsletters orother publications, nor for any decisions or actions taken in reliance on such content. --------------------------------------------------------------------------------------------- This news story was printed from *Doctor's Guide to the Internet*located at http://www.docguide.com To receive further medical news, please register for our free weekly newsletterat http://www.pslgroup.com/visitors/dgemail.htm ---------------------------------------------------------------------------------------
 
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