I was wondering the same thing. I have been taking zelnorm for about 5 weeks now and my C and bloating are gone, but I still get D about an hour after I take my zelnorm. If I don't take it I don't go at all. So it is D or nothing. Also my doctor said after 3 months on zelnorm I will have to wean myself off it. Kind of sounds like a laxtive to me. But if it safe to use I would be happy to take it for ever because I feel great when I am using it.