I took Zoloft for over a year, because I had developed anxiety attacks triggered by menopause (dizziness, tingling, insomnia, internal shaking, weakness and fatigue). Zoloft stopped the anxiety and associated problems. I have IBS-C, and sometimes D. But Zoloft didn't cause any problems with my IBS except for the first few days when I had excess gas and bloating. Some people do have digestive symptoms on Zoloft, though.The main reason I got off Zoloft was because I kept gaining weight, had no sense of libido, and developed hand tremors. And I often felt jittery during the day at work. Tapering off Zoloft was difficult for me. I had withdrawal symptoms for weeks (ringing ears, aching muscles, dizziness and visual lag, heavy fatigue, a shaky feeling inside). But eventually I got off it and now take a very small dose of Xanax when I need it, usually at bedtime. No side effects at that low dosage. that works much better for me. The thing is, not everyone responds to medications the same way. You might want to try Zoloft for just a short time and see how it works for you.