My Doc prescribed me ZYPREXA (OLAZANPINE).ZYPREXA is USUSALLY an anti-psychotic drug with some anti-depressif effect (weak).It's an 5-HT2 antagonist[b/] and also a Dopamine antagosnist (5HT-1, 5HT-3, 5HT-4 receptors are not involved). I read that even with low dose (2.5mg) all 5HT-2 receptors are occupied by the drug and not all D receptors are occupied (PET scan study).I had D with pain.This drug CLEARED my D and pain to a large extend. I use actually 2.5 mg. My doc prescribe 5 mg.One benefit (if i can say that) also is an increased appetite. So i gained some weight, not a lot. I just have to control my appetite.This effect is ALSO seen on peoples with no IBS.--SO this drug HAS effect on the gastro-intestinal track.--The first week you may experience dizziness, drozziness, ..etc as with anti-depressive drug.Check here www.rxlist.com and type Zyprexa for drug search.----I thing that it does the job via 5HT-2 receptor.That all i wanted to say.You may ask you doc.I cut the 5mg pill in 4 quarters to start it's use instead of jumping right in the max dose. So the unwanted effect are reduced. I take it by 9 P.M.I'm male so i don't know the effect on female.----Good luck
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