tezbear:My understanding is that, if you take calcium carbonate with a meal, it's a source of calcium just like it would be if you drank milk with the meal.Take calcium carbonate about 2 hours after a meal for the antacid properties.The main difference seems to be how much magnesium is in it. Different bottles of Caltrate have differing amounts of magnesium. I take the one with just calcium carbonate and Vit. D because I have never had a problem with constipation. In fact, I'm not sure that I know what constipation feels like. The more of a problem that you have with constipation, the more magnesium you would want with your calcium carbonate preparation.If you are taking the calcium carbonate for the bone density, like I do, then take it with a meal and take Vit. D with it (like caltrate). Without the Vit D, the calcium may not get absorbed properly.A couple of years ago, Consumer Reports tested calcium supplements. I think that they recommended TUMS. However, TUMS has glycerine in it (for constipation). Consumers was not impressed with the expensive forms of calcium that are sold by the drug companies. They were not absorbed as readily as the plain ones. No apparent advantage to paying more money. The expensive ones are made out of crushed egg shells.If you have questions, Linda, on this broad, is an expert on Calcium. She's really good about returning e-mails to people who have questions. I believe that she goes by "LNAPE."Hope that this helps.echris